News

Mice that were given a vitamin lived longer and were able to regenerate their organs as if they were young again.

By Zoe Demarco

Scientists say that they have found evidence that an already-celebrated vitamin can stop the aging process of organs in mice. It could also have the potential to treat degenerative diseases in humans.

Called nicotinamide riboside (NR for short), the vitamin was given to elderly mice. Compared to their non-vitamin taking counterparts, the mice were better able to regenerate their muscles and organs. They also lived longer.

The study was published Thursday in the journal Science.

As humans, mice, and other mammals age, our muscles and organs are less able to regenerate and repair themselves when they’re damaged. This leads to many common age-related disorders, according to Medical Xpress.

Gavin Young/Calgary Herald

Gavin Young/Calgary HeraldNicotinamide riboside has also been shown to regenerate brain and skin cells.

The scientists, from Switzerland, Brazil, and the University of Ottawa, first looked at how mitochondria change with age. Mitochondria, often called the “powerhouse of the cell,” are the parts that keep it full of energy. The scientists found that the mitochondria’s ability to function properly was important for stem cells — the cells responsible for regeneration — to stay healthy as well.

“We demonstrated that fatigue in stem cells was one of the main causes of poor regeneration or even degeneration in certain tissues or organs,” Hongbo Zhang, one of the authors of the study, told Medical Xpress.

This is where nicotinamide riboside comes in. It’s a precursor to a molecule called nicotinamide adenine dinucleotide (NAD+ for short), which helps mitochondria function.

So, basically, nicotinamide riboside helps to form NAD+. NAD+ keeps the mitochondria working. The mitochondria keeps stem cells healthy. And stem cells help our organs to regenerate.

NR is closely related to heart-healthy vitamin B3. Other studies have shown that it has the ability to boost metabolism and has the same regenerative abilities on the brain and skin cells.

“This work could have very important implications in the field of regenerative medicine,” said Johan Auwerx, head of the study. “We are not talking about introducing foreign substances into the body but rather restoring the body’s ability to repair itself with a product that can be taken with food.”

While the study produced no negative side effects in the mice, the regenerative effects apply to all cells, even harmful ones such as those that cause dementia. Further studies are planned, said Medical Xpress.

0 628
This simple pizza-like dish gets a tremendous amount of flavour from onions, which are cooked slowly in a small amount of bacon fat.

SARA MOULTON, THE ASSOCIATED PRESS

Back in the ’80s and ’90s, I used to work behind the scenes with Julia Child during her appearances on “Good Morning America.” It was my job to prepare the food she would put before the cameras.

Once, when I knew in advance that I couldn’t be there for one of her upcoming appearances, I invited a pal of mine — a culinary professional — to try out for the gig. We prepped the food as usual, and at the end of the day I thought my friend had done a dandy job. Julia flatly disagreed and said she wouldn’t hire her. I was flabbergasted. “Why not?” I asked.

“Because she sliced the onions the wrong way,” Julia replied.

Yikes! I simply hadn’t focused on how my friend sliced the onions. I didn’t think this detail was that important. But all these years later, I realize Julia was right. Exactly how you slice an onion makes a difference. So does how you cook it.

Everyone knows that chopping onions can literally bring tears to your eyes. Here’s why. When an onion’s cells are ruptured, they give off pungent sulfur fumes. The more roughly an onion is treated — such as when it is chopped with a dull knife or pulsed in a food processor — the more fumes it gives off.

There are any number of quaint folk remedies for this problem. Put a piece of bread in your mouth while you’re chopping. Do your chopping near a running faucet. And so on. None of them works.

What does work — at least when you’re chopping up a lot of onions — is wearing onion goggles. Modeled on welder’s goggles, these babies prevent the onion’s fumes from reaching your eyes. But the best everyday tactic is to chop or slice the onion quickly and with a very sharp knife. Chilling the onion for an hour or two ahead of time also is a good idea.

Having managed to blunt an onion’s ability to bring you to tears, let’s turn to the correct way to slice one, a la Julia. Lengthwise, not crosswise, is the way to roll. Cutting an onion in half through the root end and then slicing it from stem to stern stimulates far fewer sulfur fumes. These lengthwise slices also happen to hold together much better than crosscut slices, precisely because you’ve sliced with the grain instead of against it. This is especially important for a dish like onion soup, when you want the slices to maintain their shape.

Finally, we come to how to cook an onion, which affects not just the flavour of the onion, but of the whole dish. If you throw it into a hot pan and quickly saute it over high heat, the onion and the dish it’s added to will be bland. If you do it slowly over low heat, you’ll maximize the onion’s flavour.

All of these tips apply to making my Alsatian onion pie. The French call it tarte flambee. The Germans call it Flammkuchen. It strikes me as more like a pizza than anything else. I tasted it for the first time on a river cruise in France a couple years ago, and I was really knocked out by its combination of simplicity and big flavour. Accompanied by a fresh salad, this treat would make the perfect light supper for the beginning of spring.

ALSATIAN ONION PIE
Start to finish: 1 hour 15 minutes

6 oz bacon, thinly sliced crosswise
4 cups thinly sliced yellow onion
kosher salt and ground black pepper
8 oz creme fraiche
1 large egg yolk
pinch nutmeg
1 1/2-lb ball purchased pizza dough, room temperature
3 oz coarsely grated Gruyere cheese

1. In a large skillet over medium, cook the bacon, stirring, until it starts to brown, 5 to 8 minutes. Transfer the bacon to paper towels to drain and pour off all but 2 tablespoons of the fat from the skillet. Return the skillet to medium heat and add the onions. Cook, covered, stirring occasionally, until very soft, about 10 minutes. Remove the cover and cook, stirring occasionally, until golden, about another 30 minutes. Season with salt and pepper, then set aside.
2. Heat the oven to 500°F. Arrange one of the oven racks on the oven’s bottom shelf.
3. In a small bowl, stir together the creme fraiche, egg yolk, nutmeg and a pinch each of salt and pepper.
4. Divide the dough into 3 even pieces. On a lightly oiled surface, roll out each piece into a 10-by-12-inch rectangle about 1/8-inch thick. Transfer each to a 15-by-17-inch sheet of kitchen parchment. The dough may shrink and lose its shape. If so, roll it again on the parchment.
5. One at a time, transfer each piece of parchment and dough to a bak sheet (unless your oven can fit 2 sheets on one shelf, you’ll need to bake these one at a time). Spread a third of the creme fraiche mixture over the piece of dough on the baking sheet, then top with a third of the onions and bacon. Sprinkle with a third of the cheese, then bake on the oven’s lower shelf for 10 minutes, or until the crust is crisp. Repeat with remaining dough and toppings. Serve right away.
makes three 10- to 12-inch pizzas

Nutrition information per half pizza: 640 calories; 310 calories from fat (48 per cent of total calories); 35 g fat (16 g saturated; 0 g trans fats); 120 mg cholesterol; 1260 mg sodium; 60 g carbohydrate; 4 g fibre; 6 g sugar; 17 g protein.

0 594

Singh, 27, named in Hollywood and entertainment category

CBC News

Toronto YouTube sensation Lilly Singh, a.k.a Superwoman, has hit another career milestone, making it on the Forbes 30 under 30 list.

The 27-year-old Canadian comedian was named in the Hollywood and Entertainment category.

Singh’s Superwoman YouTube channel features her standup act, and has over 7.5 million subscribers.

This isn’t the first time Singh has landed on a Forbes list.

Last year, the comedian made it on the Forbes list of YouTube millionaires.

Toronto’s Lilly Singh makes Forbes 30 Under 30 list. (Rick MatharuThe Canadian Press)

Singh was eighth on the list, earning $2.5 million.

She shared eighth place with prankster Roman Atwood and chef Rosanna Pansino.

Last year, Singh took her act on the road with a North American tour, with a stop in Toronto in June at the Danforth Music Hall.

Two other Toronto personalities have joined Singh on the list. They are musicians Shawn Mendes, 17, and The Weeknd, 25.

 

Washington D.C., Nov. 18 (ANI): Val Kilmer might be reprising his role as ‘Iceman’ in ‘Top Gun 2.’

The 55-year-old actor posted a message on his Facebook wall, saying “I just got offered Top Gun 2 – not often you get to say ‘yes’ without reading the script,” Us Weekly reported.

Kilmer also said that an actor should say ‘yes’ when they have an option to work with Tom Cruise, Gene Hackman, and Francis Coppola. However, the actor later clarified that Coppola and Hackman were not involved in the sequel.

Kilmer played the role of `Iceman` in 1986’s Top Gun alongside Cruise, Kelly McGillis, and Anthony Edwards.

0 1026

By- Mehak Sabharwal

New Delhi, Nov. 18(ANI): Like many other leading ladies in the tinsel town, Kalki Koechlin also wishes to work with the Khans and when it comes to the traditional loves stories, she would definitely try her hand in one.

When asked about her dream cast, the 31-year-old actress told ANI that she would love to work with the Khans, especially with Shah Rukh Khan because she thinks he is fantastic and charming as well.

Talking about her dream director, the ‘Margarita With a Straw’ star revealed that Vishal Bhardwaj tops her list because she thinks he is a fine blend of both artistic alternatives and commercial cinema.

Kalki, who strongly believes in the Japanese saying, “‘Today better than yesterday worst that tomorrow,” also said that she would like to try her hand in traditional love stories because for her, it’s not about not wanting to do commercial roles, it’s about fitting in and doing something she can pull off convincingly.

Further, when the thespian actress was asked if she would like to wear a director’s hat some day, she joked that she doesn’t have spare money in her pocket.

Kalki will be next seen in Nicholas Kharkongor’s directorial ‘Mantra’ alongside Shiv Pandit and Rajat Kapoor. She will be seen in the character of Rajat’s rebellious daughter, who always wants more from life.

Washington D.C., Nov. 18 (ANI): After Charlie Sheen admitted to being HIV positive, many celebrities have come forward to support his decision to go public with his illness.

Pop star Lady Gaga posted a picture on Instagram, in which the actor is seen talking to Matt Lauer on ‘The Today Show,’ captioning it “#BraveCharlie @btwfoundation, an opportunity for people all over the world to learn about modern HIV prevention, treatments, and emotional intelligence as it relates to the stigma of the virus,” E!Online reports.

Journalist Piers Morgan shared a picture on twitter, in which he is seen interviewing the actor and captioned it, saying “Bravo @charliesheen – that took guts today. Proud to be your mate.”

‘Two and a Half Men’ actress Heather Locklear shared an old picture with the star on Instagram, captioning “My heart hurts. Prayers for Charlie and his family.”

During an interview on ‘The Today Show,’ the 51-year-old actor had admitted that he was HIV positive and said that he was diagnosed four years ago.

TORONTO: Manasvi Noel of Mississauga City has been crowned Miss India-Canada 2015 at the 25th edition of the annual beauty pageant organised here, a media report said.

During a night full of “entertainment, prestige and glamour all rolled up into one”, the Dubai-born Noel won the esteemed title, the final top contenders for which included Sharon Philipose, Kajill Aujila, Tanpreet Parmar and Priya Sharma, Canada-based the VOICE reported on Tuesday.
Sharon Philipose was adjudged the first runner-up, while Kajill Aujila was the first runner-up of the contest held during the weekend at the International Plaza Hotel here. This year marked the silver jubilee of the beauty pageant.

Organisers Sanjay Agnihotri and Gautam Sharma also presented the Special Achievement Award to Bollywood actress Preity Zinta for her contribution to Indian and international cinema.
Noel, a graduate from CIMT College’s Etobicoke School of the Arts in drama and acting, is currently studying media communications at Toronto’s Humber College.
She plans to have her own academy for freestyle dancing in which students can learn different Indian and traditional dance forms.

0 493

BY POSTMEDIA NEWS
Much has been written and said about changes to the Elections Act that will affect voters. New identification rules mean you won’t be able to use your voter card as ID; vouching for other voters will be restricted; and the role of Elections Canada has been changed. Some of these changes have been challenged in the courts.

Other changes to the Elections Act, passed into law recently with the Fair Elections Act, means we can likely expect an early start to the election period. With the first debate of all the federal leaders set for Aug. 6, don’t be surprised to hear the election has been called shortly after. Here is why.

1. The longer the campaign goes, the more money parties and candidates can spend, and they get 50 per cent of whatever they spend from taxpayers.

The spending limit on past elections was fixed. This time, every additional day above 37 days, the party and candidates can spend an additional 1/37th of that limit. That is approximately $685,000 a day for the party and over $900,000 a day for the candidates in all 338 ridings combined. For example, if the election starts on Aug. 10, an additional 29 days, the total party spending limit would go from $25 million to $45 million and total riding limits would increase from $34 million to more than $60 million. A combined $105 million per party. Although per-vote subsidies have been eliminated, the rebates that parties and local campaigns receive will mean the taxpayer could be on the hook for up to $53 million per party after this election, this on top of the estimated $300 million it costs to run the election itself.

2. Local riding associations/candidates cannot get loans.

In the past, when a candidate or local district association did not have the money raised to run a campaign, they could go to a bank and get a loan. Under the new rules, a loan can only be guaranteed by individuals who are not already donors, and to a maximum of $1,500. To get a $30,000 loan (a bare-bones campaign in most ridings), a candidate would need to find 20 individuals willing to sign for their $1,500 share of the loan. This is an advantage to district associations and candidates with more money raised; candidates who walk into the writ period with little fundraising could face a big challenge in meeting expenses.

3. A party can transfer money to a district association, and a district association can transfer money to another district association.

There are district associations that have a lot of money, more than they could possibly spend in a single election or two. There are also district associations that have less money who can accept transfers from either the central party, or from those richer associations. The cumulative effect of spending on advertising, signs, flyers, staff and other resources will be a tremendous advantage to the party with the most to spend.

4. There will be more numerous and more varied advertising.

Expect to see more ads, and different types of ads, in this election, as campaigns target segments of the population with issue-specific ads, or based on regional and local issues. In the 2004 election, you could expect to see five to 10 ads run nationally per party. As production technology becomes cheaper, we can expect dozens of ads online, on TV, or both. With district association limits now exceeding $200,000 and many costs fixed, expect to see more local and regional advertising.

5. Third party advertisements and PAC spending are limited during the writ.

Until the election is called, there are few rules on third parties. Political Action Committees (PACs) and other third parties can spend as much as they want to support their agenda. Once the writ of election is issued, spending limits become much more restrictive. A third party can spend a total of $205,800 across Canada during a 37-day campaign, and no more than $4,116 in any riding. Similar to the party and riding limits, this increases by 1/37th for every day the election is above 37 days. Even if the election is twice as long as that, the limits would increase by a fraction of increase to party and candidate limits. If there are more PACs opposing the current government than supporting it, an early election call will benefit the government.

The call of the election is of course up to one person, the current prime minister. Despite the fixed election date law, there are no rules on how long the campaign leading up to election day can be. With so many clear advantages to the party with the most money to spend, it’s not likely we will see a standard 37-day election.

As most of us enjoy the Civic Holiday with friends and family this Aug. 3, the federal parties will be gassing up the planes, polishing the campaign buses and dusting off their signs. Some of you may choose to ignore the campaign until after Thanksgiving, but hopefully the extra $75 million (give or take) it’s costing us this time will be enough motivation for more of us to get out and vote.

Quito Maggi is the CEO of Mainstreet Research